KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EP300
All Species:
23.94
Human Site:
S946
Identified Species:
43.89
UniProt:
Q09472
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09472
NP_001420.2
2414
264161
S946
P
L
S
Q
P
A
V
S
I
E
G
Q
V
S
N
Chimpanzee
Pan troglodytes
XP_515155
2411
263753
S946
P
L
S
Q
P
A
V
S
I
E
G
Q
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001102844
2414
264251
S946
P
L
S
Q
P
A
V
S
I
E
G
Q
V
S
N
Dog
Lupus familis
XP_851777
2404
260682
S932
P
L
S
Q
A
A
A
S
I
D
N
R
V
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S968
P
L
S
Q
A
A
A
S
I
D
N
R
V
P
T
Rat
Rattus norvegicus
XP_001076610
2413
263563
E946
S
Q
P
A
V
S
V
E
G
Q
V
S
N
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233888
2444
267496
S957
P
L
S
Q
P
A
V
S
I
D
G
Q
V
S
N
Frog
Xenopus laevis
NP_001088637
2428
264402
T972
S
V
D
N
H
V
R
T
P
A
S
V
A
S
T
Zebra Danio
Brachydanio rerio
XP_001332718
2667
289125
E954
P
A
S
V
S
S
V
E
A
S
F
Q
Q
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
S1501
A
T
T
T
T
S
T
S
S
S
S
R
M
M
S
Honey Bee
Apis mellifera
XP_001122031
2606
284119
M1144
L
A
S
L
G
K
G
M
T
S
Q
E
R
A
A
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
S791
D
Q
N
T
D
S
L
S
S
R
P
P
T
A
I
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
E1193
G
K
G
Y
I
K
Q
E
S
S
S
T
S
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
61
N.A.
58.6
94.1
N.A.
N.A.
85.1
60.4
57
N.A.
36.2
43
31.1
39.5
Protein Similarity:
100
99.7
99.5
72.4
N.A.
69.5
96.1
N.A.
N.A.
89.9
71
65.9
N.A.
46.6
54.9
45.6
51.5
P-Site Identity:
100
100
100
53.3
N.A.
53.3
6.6
N.A.
N.A.
93.3
6.6
26.6
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
66.6
N.A.
66.6
20
N.A.
N.A.
100
20
40
N.A.
40
20
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
16
47
16
0
8
8
0
0
8
31
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
0
0
24
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
24
0
24
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
8
0
8
0
8
0
8
0
31
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
47
0
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
16
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
47
0
8
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
16
0
8
0
31
% N
% Pro:
54
0
8
0
31
0
0
0
8
0
8
8
0
24
24
% P
% Gln:
0
16
0
47
0
0
8
0
0
8
8
39
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
24
8
0
0
% R
% Ser:
16
0
62
0
8
31
0
62
24
31
24
8
8
39
8
% S
% Thr:
0
8
8
16
8
0
8
8
8
0
0
8
8
0
24
% T
% Val:
0
8
0
8
8
8
47
0
0
0
8
8
47
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _